AN ISOTHERMAL, NON-ENZYMATIC, AND DUAL-AMPLIFIED FLUORESCENT SENSOR FOR HIGHLY SENSITIVE DNA DETECTION



Preclinical evidence for employing MEK inhibition in NRAS mutated pediatric gastroenteropancreatic neuroendocrine-like tumors

Background: Pediatric gastroenteropancreatic neuroendocrine tumors are exceedingly rare, resulting in most pediatric treatment recommendations being based on data derived from adults.Trametinib is a kinase inhibitor that targets MEK1/2 and has been employed in the Service treatment of cancers harboring mutations in the Ras pathway.Methods: We utili

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From local landscapes to international policy: contributions of the biocultural paradigm to global sustainability

Nature and culture are intricately linked and the rapid loss of both biological and cultural diversity around the globe has led to increasing concerns about its effects on sustainability.Important efforts to understand biocultural relations and bolster sustainable practices have been made bottoms by scientists, local communities, civil society orga

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